BacMap: Bacterial Genome Atlas

Pseudomonas aeruginosa

Image source: http://www.astrosurf.com/lombry/Bio/pseudomonas-aeruginosa.png

Species
Pseudomonas aeruginosa

Kingdom
Bacteria

Taxonomy
Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas; Pseudomonas aeruginosa group; Pseudomonas aeruginosa

Strains
PAO1

Gram Stain
Negative

Accession Numbers
PAO1:
NC_002516

Genome
PAO1:
Chromosome: 6,264,403 bp
Plasmid pf3: 5,833 bp
Plasmid pf3ny: 5,833 bp

Background
Pseudomonas aeruginosa are motile, mesophilic, Gram-negative rod bacterium that are noted for their environmental versatility. P. aeruginosa is increasingly recognised as a nosocomial pathogen, targetting immunocompromised individuals, cancer and burn victims, and individuals with in-dwelling catheters or using respirators. It is also the leading cause in mortality and morbidity for cystic fibrosis patients.

Unlike many environmental bacteria, P. aeruginosa has the ability to adapt to and thrive in many ecological niches, from water and soil to plant and animal tissues. The bacterium is capable of utilising a wide range of organic compounds as food sources, thus giving it an exceptional ability to colonise where nutrients are limited.

P. aeruginosa can produce a number of toxic proteins which not only cause extensive tissue damage, but also interfere with the human immune system's defense mechanisms. These proteins range from potent toxins that enter and kill host cells at or near the site of colonisation to degradative enzymes that permanently disrupt the cell membranes and connective tissues in various organs.

(From http://www.ebi.ac.uk/2can/genomes/bacteria.html)

Sequenced By
PAO1:
PathoGenesis Corporation, Seattle, Washington 98119, USA.

Sequence Publications
PAO1:
Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, Hickey MJ, Brinkman FS, Hufnagle WO, Kowalik DJ, Lagrou M, Garber RL, Goltry L, Tolentino E, Westbrock-Wadman S, Yuan Y, Brody LL, Coulter SN, Folger KR, Kas A, Larbig K, Lim R, Smith K, Spencer D, Wong GK, Wu Z, Paulsen IT, Reizer J, Saier MH, Hancock RE, Lory S, Olson MV., Nature 406(6799):959-64 (2000 Aug 31).

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